Vitamin C Before and After Surgery

Practitioner Guidance

Collagen Production and Immune Support

Vitamin C plays a crucial role in the formation of collagen, a major component of our connective tissue. Collagen is found in skin, ligaments, tendons, cartilage, bones, blood vessels, intestines, spinal discs, corneas and muscles.

In any episode of trauma, including planned surgery, tissues are damaged. During repair collagen must be formed – so an abundant supply of vitamin C is needed.

Vitamin C is also important in the proper functioning of the immune system. Surgery and anaesthesia cause physical stress and this may have adverse effects on the immune system.

What the Research Says

Vitamin C can reduce the need for pain relief after surgery. 1

In orthopaedic surgery there is evidence that complex regional pain syndrome can be avoided with adequate vitamin C levels. 2

During and after surgery, vitamin C levels in the body are measurably decreased and replacement above the normal dietary recommendations is necessary to correct this. 3


1) Effect of Intravenous High Dose Vitamin C on Postoperative Pain and Morphine Use after Laparoscopic Colectomy: A Randomized Controlled Trial. Pain Research and Management.

2) Effect of Perioperative Vitamin C Supplementation on Postoperative Pain and the Incidence of Chronic Regional Pain Syndrome: A Systematic Review and Meta-Analysis. The Clinical Journal of Pain.

3) Vitamin C requirement in surgical patients. Current Opinion in Clinical Nutrition & Metabolic Care.

The information provided here is only for general reference and cannot replace personalised professional medical advice from a doctor.

Introductory Material

The following articles cover our main products and a sample of conditions. For more detailed materials, please refer to our Knowledge Base.

Vitamin C

EDTA Chelation